Publications on HPTLC
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A sensitive HPTLC-EDA method using a 4-MU fluorescent probe for AChE inhibitor screening
February 17, 2026
This study, conducted by researchers at Université Clermont Auvergne (ICCF, CNRS, France), presents a new HPTLC-EDA method using a 4-methylumbelliferone (4-MU) fluorogenic probe for sensitive screening of acetylcholinesterase (AChE) inhibitors. The method provides over threefold higher sensitivity, fewer artefacts, and improved detection of bioactive compounds in complex natural extracts, offering a simple and reliable tool for bioactivity screening.
Maël Gainche, Norberta Delporte, Clément Michelin, Elodie Jagu (Université Clermont Auvergne)
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