Skip to main content

Cumulative CAMAG
Bibliography Service CCBS

Welcome to the Cumulative CAMAG Bibliography Service (CCBS) – your comprehensive resource for HPTLC literature. CCBS offers an up-to-date, searchable database of publications, technical papers, and application notes, curated to support research and innovation in High-Performance Thin-Layer Chromatography.

12 805+

abstracts of publications
 1983 -> today

12 805 abstracts found.
Simultaneous determination of amlodipine besylate and azilsartan mixture in human plasma utilizing high-performance thin-layer chromatography with ultraviolet detection
A. KHORSHED*, F. ABDELNAEEM, S. DERAYEA, M. ORABY, D. NAGY (*Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Sohag University, Sohag 82524, Egypt, ahmed_khorshed@pharm.sohag.edu.eg)

J. Planar Chromatogr. 37, 261-269 (2024). HPTLC of amlodipine besylate (1) and azilsartan (2) mixture in human plasma on silica gel with toluene - ethyl acetate - methanol - acetone - acetic acid 12:3:2:1:2. Quantitative determination by absorbance measurement at 244 nm. The hRF values for (1) and (2) were 22 and 63, respectively. Linearity was between 60 and 600 ng/zone for (1) and 90 and 900 ng/zone for (2). The inter-day and intra-day precision was below 3 % (n=6). The LOD and LOQ were 14 and 42 ng/zone for (1) and 19 and 56 ng/zone for (2), respectively. Recovery was between 99.1 and 102.2 % for (1) and (2).

Classification:
32. Pharmaceutical and biomedical applications
a) Synthetic drugs
Simultaneous estimation of lupeol, stigmasterol and botulin in Desmodium oojeinensis bark and roots by a validated instrumental thin-layer chromatography method
S. INGOLE, B. GHULE*, K. PATIL, N. TAKALE (*Department of Pharmacognosy, Government College of Pharmacy, Kathora Naka, Amravati, Maharashtra State 444 604, India, ghulebv@rediffmail.com)

J. Planar Chromatogr. 37, 207-218 (2024). HPTLC of lupeol (1), stigmasterol (2) and betulin (3) in the bark and roots of Desmodium oojeinensis on silica gel with hexane - ethyl acetate 17:3. Detection by spraying with anisaldehyde - sulfuric acid reagent, followed by heating at 105 °C for 3-5 min. Quantitative determination by absorbance measurement at 520 nm. The hRF values for (1) to (3) were 41, 27 and 19, respectively. Linearity was between 200 and 600 ng/zone for (1) to (3). The inter-day and intra-day precision was below 2 % (n=6). The LOD and LOQ were 13 and 39 ng/zone for (1), 18 and 55 ng/zone for (2) and 13 and 41 ng/zone for (3), respectively. Average recovery was 97.4 % for (1), 97.7 % for (2) and 97.0 % for (3).

Classification:
13. Steroids
c) Sterols
14. Steroid glycosides, saponins and other terpenoid glycosides
Evaluation and observance of variation in chemical and antioxidant activity changes during the development of fenugreek seeds following thin-layer chromatography-fingerprint and marker analysis
J. DAHIYA*, D. KUMAR, K. HAZRA, R. BOLLEDDU, S. DUTTA, S. MALL, D. GHOSH, A. MANGAL, G. BABU (*Department of Pharmacognosy, Central Ayurveda Research Institute, CCRAS, Ministry of AYUSH, Kolkata, West Bengal 700091, India, jyotidahiya31@gmail.com)

J. Planar Chromatogr. 37, 247-260 (2024). HPTLC of diosgenin in fenugreek seeds on silica gel with toluene - ethyl acetate 9:1. Detection by spraying with anisaldehyde - sulfuric acid reagent, followed by heating at 105 °C for 3-5 min. Quantitative determination by absorbance measurement at 560 nm. The hRF value for diosgenin was 20. Linearity was between 2 and 10 ng/zone. The inter-day and intra-day precision was below 2 % (n=6). The LOD and LOQ were 0.56 and 1.69 ng/zone. Recovery was between 97 and 99 %.

Classification:
14. Steroid glycosides, saponins and other terpenoid glycosides
Unraveling the anti-obesity potential of Haldina cordifolia bioactive fractions in 3T3-L1 adipocytes differentiation: in vitro, high-performance thin-layer chromatography-multistage mass spectrometry and in silico studies
S. KUMARI, A. PATTNAIK* (*Department of Pharmaceutical Sciences and Technology, Birla Institute of Technology, Mesra, Ranchi, India, ashokp@bitmesra.ac.in)

J. Planar Chromatogr. 37, 283-297 (2024). HPTLC of caffeine (1), quercetin (2), ß-sitosterol (3), naringin (4) and ascorbic acid (5) on silica gel with toluene - ethyl acetate 3:2. Detection by spraying with anisaldehyde - sulfuric acid reagent, followed by heating at 110 °C for 15 min. Qualitative determination under UV light at 254 and 355 nm. Further analysis using a TLC-MS interface. The hRF values for (1) to (4) were 82, 65, 57, 44 and 26, respectively.

Classification:
08. Substances containing heterocyclic oxygen
a) Flavonoids
13. Steroids
c) Sterols
Identification of acetylcholinesterase inhibitory metabolites from hydroalcoholic extract of Itrifal Muqawwi Dimagh using thin-layer chromatography-bioautography-mass spectroscopy and its validation using in silico molecular approach
M. SAMAL, A. SIDDIQUI, V. SRIVASTAVA, M. DAR, M. KHAN, A. INSAF, S. ANSARI, S. AHMAD* (*Centre of Excellence in Unani Medicine, Bioactive Natural Product Laboratory, Department of Pharmacognosy and Phytochemistry, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi 110062, India, sahmad_jh@yahoo.co.in)

J. Planar Chromatogr. 37, 271-282 (2024). HPTLC of the traditional polyherbal formulation Itrifal Muqawwi Dimagh (IMD) on silica gel with chloroform - methanol 9:1. Detection by spraying with 5 % anisaldehyde - sulfuric acid in methanol reagent. Qualitative determination under UV light at 254 and 366 nm. Bioautography for the determination of anticholinesterase active metabolites by spraying with the substrate, dye, and enzyme. DTNB/ATCI reagent (1 mmol/L DTNB and 1 mmol/L ATCI in buffer A).

Classification:
32. Pharmaceutical and biomedical applications
e) Plant extracts, herbal and traditional medicines
Filter by
CCBS classifications

Need some help?

Enjoy faster, more accurate analyses, reduced costs, and improved results. We are here to make it happen