The global fight against the COVID 19 pandemic has moved mRNA vaccines on the center stage. The mRNA technology utilizes lipid-based formulations as a drug delivery system. To protect the fragile mRNA molecules from degradation, they are commonly encapsulated in liposomes or lipid nanoparticles.
CAMAG has released an application note on the analysis and quality control of lipid-based formulations by HPTLC. This methodology demonstrates an efficient approach for identification and stability testing of lipids and lipid-based formulations.